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Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

The lipophilic polycyclic aromatic hydrocarbon (PAH) phenanthrene is relatively abundant in polluted air and water and can access and accumulate in human tissue. Phenanthrene has been reported to interact with cardiac ion channels in several fish species. This study was undertaken to investigate the...

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Detalles Bibliográficos
Autores principales: Al-Moubarak, Ehab, Shiels, Holly A., Zhang, Yihong, Du, Chunyun, Hanington, Oliver, Harmer, Stephen C., Dempsey, Christopher E., Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629796/
https://www.ncbi.nlm.nih.gov/pubmed/34727194
http://dx.doi.org/10.1007/s00018-021-03967-8