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Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns

Motivational symptoms such as anergia, fatigue, and reduced exertion of effort are seen in depressed people. To model this, nucleus accumbens (Nacb) dopamine (DA) depletions are used to induce a low-effort bias in rodents tested on effort-based decision-making. We evaluated the effect of the catecho...

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Detalles Bibliográficos
Autores principales: Carratalá-Ros, Carla, Olivares-García, Régulo, Martínez-Verdú, Andrea, Arias-Sandoval, Edgar, Salamone, John D., Correa, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629809/
https://www.ncbi.nlm.nih.gov/pubmed/34498115
http://dx.doi.org/10.1007/s00213-021-05950-4