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The Na(+)-activated K(+) channel Slack contributes to synaptic development and plasticity

Human mutations of the Na(+)-activated K(+) channel Slack (KCNT1) are associated with epilepsy and intellectual disability. Accordingly, Slack knockout mice (Slack(−/−)) exhibit cognitive flexibility deficits in distinct behavioral tasks. So far, however, the underlying causes as well as the role of...

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Detalles Bibliográficos
Autores principales: Matt, Lucas, Pham, Thomas, Skrabak, David, Hoffmann, Felix, Eckert, Philipp, Yin, Jiaqi, Gisevius, Miriam, Ehinger, Rebekka, Bausch, Anne, Ueffing, Marius, Boldt, Karsten, Ruth, Peter, Lukowski, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629810/
https://www.ncbi.nlm.nih.gov/pubmed/34664085
http://dx.doi.org/10.1007/s00018-021-03953-0