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The Na(+)-activated K(+) channel Slack contributes to synaptic development and plasticity
Human mutations of the Na(+)-activated K(+) channel Slack (KCNT1) are associated with epilepsy and intellectual disability. Accordingly, Slack knockout mice (Slack(−/−)) exhibit cognitive flexibility deficits in distinct behavioral tasks. So far, however, the underlying causes as well as the role of...
Autores principales: | Matt, Lucas, Pham, Thomas, Skrabak, David, Hoffmann, Felix, Eckert, Philipp, Yin, Jiaqi, Gisevius, Miriam, Ehinger, Rebekka, Bausch, Anne, Ueffing, Marius, Boldt, Karsten, Ruth, Peter, Lukowski, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629810/ https://www.ncbi.nlm.nih.gov/pubmed/34664085 http://dx.doi.org/10.1007/s00018-021-03953-0 |
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