OncomiRs miR-106a and miR-17 negatively regulate the nucleoside-derived drug transporter hCNT1

High-affinity uptake of natural nucleosides as well as nucleoside derivatives used in anticancer therapies is mediated by human concentrative nucleoside transporters (hCNTs). hCNT1, the hCNT family member that specifically transports pyrimidines, is also a transceptor involved in tumor progression....

Descripción completa

Detalles Bibliográficos
Autores principales: Boces-Pascual, Clara, Mata-Ventosa, Aida, Martín-Satué, Mireia, Boix, Loreto, Gironella, Meritxell, Pastor-Anglada, Marçal, Pérez-Torras, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629896/
https://www.ncbi.nlm.nih.gov/pubmed/34647142
http://dx.doi.org/10.1007/s00018-021-03959-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629896/
https://www.ncbi.nlm.nih.gov/pubmed/34647142
http://dx.doi.org/10.1007/s00018-021-03959-8

Ejemplares similares