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Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D(2/3) receptor signaling in a rat model of vulnerability to drug abuse

RATIONALE: Risk factors for drug addiction include genetics, environment, and behavioral traits such as impulsivity and novelty preference (NP), which have been related to deficits in striatal dopamine (DA) D(2/3)-receptors (D(2/3)R) and heightened amphetamine (AMPH)-induced DA release. However, the...

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Detalles Bibliográficos
Autores principales: Bellés, Lidia, Dimiziani, Andrea, Herrmann, François R., Ginovart, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629910/
https://www.ncbi.nlm.nih.gov/pubmed/34463825
http://dx.doi.org/10.1007/s00213-021-05971-z