Ki-67 gene expression

Ki-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are maximally expressed in G(2) phase and mitosis. Expression is dependent on two CHR elements and one CDE site in the MKI67 prom...

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Detalles Bibliográficos
Autores principales: Uxa, Sigrid, Castillo-Binder, Paola, Kohler, Robin, Stangner, Konstanze, Müller, Gerd A., Engeland, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629999/
https://www.ncbi.nlm.nih.gov/pubmed/34183782
http://dx.doi.org/10.1038/s41418-021-00823-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629999/
https://www.ncbi.nlm.nih.gov/pubmed/34183782
http://dx.doi.org/10.1038/s41418-021-00823-x

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