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MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF

The blockade of cellular differentiation represents a hallmark of acute myeloid leukemia (AML), which is largely attributed to the dysfunction of lineage-specific transcription factors controlling cellular differentiation. However, alternative mechanisms of cellular differentiation programs in AML r...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Ros, Uris, Agrawal, Deepti, Keller, Eva C., Slotta-Huspenina, Julia, Dill, Veronika, Shen, Bo, Shi, Run, Herold, Tobias, Belka, Claus, Mishra, Ritu, Bassermann, Florian, Garcia-Saez, Ana J., Jost, Philipp J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630008/
https://www.ncbi.nlm.nih.gov/pubmed/34079078
http://dx.doi.org/10.1038/s41418-021-00811-1