Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites

The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of Plasmodium falciparum. This vaccine has limited efficacy, only preventing severe disease in about 30% of vaccinated individuals. A more efficaci...

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Detalles Bibliográficos
Autores principales: Evert, Benjamin J., Chen, Shuxiong, McConville, Robyn, Steel, Ryan W. J., Healer, Julie, Boddey, Justin A., Huntimer, Lucas, Rehm, Bernd H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630014/
https://www.ncbi.nlm.nih.gov/pubmed/34845267
http://dx.doi.org/10.1038/s41541-021-00408-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630014/
https://www.ncbi.nlm.nih.gov/pubmed/34845267
http://dx.doi.org/10.1038/s41541-021-00408-2

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