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Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites

The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of Plasmodium falciparum. This vaccine has limited efficacy, only preventing severe disease in about 30% of vaccinated individuals. A more efficaci...

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Detalles Bibliográficos
Autores principales:	Evert, Benjamin J., Chen, Shuxiong, McConville, Robyn, Steel, Ryan W. J., Healer, Julie, Boddey, Justin A., Huntimer, Lucas, Rehm, Bernd H. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630014/ https://www.ncbi.nlm.nih.gov/pubmed/34845267 http://dx.doi.org/10.1038/s41541-021-00408-2

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