Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation

Within the bone marrow microenvironment, endothelial cells (EC) exert important functions. Arterial EC support hematopoiesis while H-type capillaries induce bone formation. Here, we show that BM sinusoidal EC (BM-SEC) actively control erythropoiesis. Mice with stabilized β-catenin in BM-SEC (Ctnnb1(...

Descripción completa

Detalles Bibliográficos
Autores principales: Heil, Joschka, Olsavszky, Victor, Busch, Katrin, Klapproth, Kay, de la Torre, Carolina, Sticht, Carsten, Sandorski, Kajetan, Hoffmann, Johannes, Schönhaber, Hiltrud, Zierow, Johanna, Winkler, Manuel, Schmid, Christian David, Staniczek, Theresa, Daniels, Deborah E., Frayne, Jan, Metzgeroth, Georgia, Nowak, Daniel, Schneider, Sven, Neumaier, Michael, Weyer, Vanessa, Groden, Christoph, Gröne, Hermann-Josef, Richter, Karsten, Mogler, Carolin, Taketo, Makoto Mark, Schledzewski, Kai, Géraud, Cyrill, Goerdt, Sergij, Koch, Philipp-Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630019/
https://www.ncbi.nlm.nih.gov/pubmed/34845225
http://dx.doi.org/10.1038/s41467-021-27161-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630019/
https://www.ncbi.nlm.nih.gov/pubmed/34845225
http://dx.doi.org/10.1038/s41467-021-27161-3

Ejemplares similares