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A general strategy for C(sp(3))–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor

Photoredox catalysis has provided many approaches to C(sp(3))–H functionalization that enable selective oxidation and C(sp(3))–C bond formation via the intermediacy of a carbon-centered radical. While highly enabling, functionalization of the carbon-centered radical is largely mediated by electrophi...

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Detalles Bibliográficos
Autores principales: Leibler, Isabelle Nathalie-Marie, Tekle-Smith, Makeda A., Doyle, Abigail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630022/
https://www.ncbi.nlm.nih.gov/pubmed/34845207
http://dx.doi.org/10.1038/s41467-021-27165-z