Computer aided designing of novel pyrrolopyridine derivatives as JAK1 inhibitors

Janus kinases (JAKs) are a family of non-receptor kinases that play a key role in cytokine signaling and their aberrant activities are associated with the pathogenesis of various immune diseases. The JAK1 isoform plays an essential role in the types 1 and II interferon signaling and elicits signals...

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Detalles Bibliográficos
Autores principales: Keretsu, Seketoulie, Ghosh, Suparna, Cho, Seung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630053/
https://www.ncbi.nlm.nih.gov/pubmed/34845259
http://dx.doi.org/10.1038/s41598-021-02364-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630053/
https://www.ncbi.nlm.nih.gov/pubmed/34845259
http://dx.doi.org/10.1038/s41598-021-02364-2

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