The NUCKS1-SKP2-p21/p27 axis controls S phase entry

Efficient entry into S phase of the cell cycle is necessary for embryonic development and tissue homoeostasis. However, unscheduled S phase entry triggers DNA damage and promotes oncogenesis, underlining the requirement for strict control. Here, we identify the NUCKS1-SKP2-p21/p27 axis as a checkpoi...

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Detalles Bibliográficos
Autores principales: Hume, Samuel, Grou, Claudia P., Lascaux, Pauline, D’Angiolella, Vincenzo, Legrand, Arnaud J., Ramadan, Kristijan, Dianov, Grigory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630071/
https://www.ncbi.nlm.nih.gov/pubmed/34845229
http://dx.doi.org/10.1038/s41467-021-27124-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630071/
https://www.ncbi.nlm.nih.gov/pubmed/34845229
http://dx.doi.org/10.1038/s41467-021-27124-8

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