Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obesity-driven colonic tumorigenesis. In local colon cancer pat...

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Detalles Bibliográficos
Autores principales: Iftikhar, Rida, Penrose, Harrison M., King, Angelle N., Samudre, Joshua S., Collins, Morgan E., Hartono, Alifiani B., Lee, Sean B., Lau, Frank, Baddoo, Melody, Flemington, Erik F., Crawford, Susan E., Savkovic, Suzana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630180/
https://www.ncbi.nlm.nih.gov/pubmed/34845203
http://dx.doi.org/10.1038/s41389-021-00373-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630180/
https://www.ncbi.nlm.nih.gov/pubmed/34845203
http://dx.doi.org/10.1038/s41389-021-00373-4

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