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Expression and purification of a native Thy1-single-chain variable fragment for use in molecular imaging

Molecular imaging using singlechain variable fragments (scFv) of antibodies targeting cancer specific antigens have been considered a non-immunogenic approach for early diagnosis in the clinic. Usually, production of proteins is performed within Escherichia coli. Recombinant proteins are either expr...

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Detalles Bibliográficos
Autores principales: Jugniot, Natacha, Bam, Rakesh, Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630227/
https://www.ncbi.nlm.nih.gov/pubmed/34845270
http://dx.doi.org/10.1038/s41598-021-02445-2