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Expression and purification of a native Thy1-single-chain variable fragment for use in molecular imaging
Molecular imaging using singlechain variable fragments (scFv) of antibodies targeting cancer specific antigens have been considered a non-immunogenic approach for early diagnosis in the clinic. Usually, production of proteins is performed within Escherichia coli. Recombinant proteins are either expr...
Autores principales: | Jugniot, Natacha, Bam, Rakesh, Paulmurugan, Ramasamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630227/ https://www.ncbi.nlm.nih.gov/pubmed/34845270 http://dx.doi.org/10.1038/s41598-021-02445-2 |
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