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Molecular architecture of black widow spider neurotoxins

Latrotoxins (LaTXs) are presynaptic pore-forming neurotoxins found in the venom of Latrodectus spiders. The venom contains a toxic cocktail of seven LaTXs, with one of them targeting vertebrates (α-latrotoxin (α-LTX)), five specialized on insects (α, β, γ, δ, ε- latroinsectotoxins (LITs), and one on...

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Detalles Bibliográficos
Autores principales: Chen, Minghao, Blum, Daniel, Engelhard, Lena, Raunser, Stefan, Wagner, Richard, Gatsogiannis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630228/
https://www.ncbi.nlm.nih.gov/pubmed/34845192
http://dx.doi.org/10.1038/s41467-021-26562-8