Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages

HIV-1 replicates in cells that express a wide array of innate immune sensors and may do so simultaneously with other pathogens. How a coexisting innate immune stimulus influences the outcome of HIV-1 sensing, however, remains poorly understood. Here, we demonstrate that the activation of a second si...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mohammad Adnan, Yamashita, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630538/
https://www.ncbi.nlm.nih.gov/pubmed/34844429
http://dx.doi.org/10.1128/mBio.02817-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630538/
https://www.ncbi.nlm.nih.gov/pubmed/34844429
http://dx.doi.org/10.1128/mBio.02817-21

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