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Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes

Tonic inhibition mediated by extrasynaptic GABA(A)Rs regulates various brain functions. However, the mechanisms that regulate tonic inhibition remain largely unclear. Here, we report distinct actions of GluN2A- and GluN2B-NMDA receptors (NMDARs) on tonic inhibition in hippocampal neurons under basal...

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Detalles Bibliográficos
Autores principales: Wu, Kunwei, Castellano, David, Tian, Qingjun, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630577/
https://www.ncbi.nlm.nih.gov/pubmed/34758303
http://dx.doi.org/10.1016/j.celrep.2021.109960