Targeting TBK1 Attenuates LPS-Induced NLRP3 Inflammasome Activation by Regulating of mTORC1 Pathways in Trophoblasts

Pathological maternal inflammation and abnormal placentation contribute to several pregnancy-related disorders, including preterm birth, intrauterine growth restriction, and preeclampsia. TANK-binding kinase 1 (TBK1), a serine/threonine kinase, has been implicated in the regulation of various physio...

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Detalles Bibliográficos
Autores principales: Lee, Sohee, Shin, Jiha, Kim, Jong-Seok, Shin, Jongdae, Lee, Sung Ki, Park, Hwan-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630692/
https://www.ncbi.nlm.nih.gov/pubmed/34858401
http://dx.doi.org/10.3389/fimmu.2021.743700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630692/
https://www.ncbi.nlm.nih.gov/pubmed/34858401
http://dx.doi.org/10.3389/fimmu.2021.743700

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