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A Small Ligand That Selectively Binds to the G-quadruplex at the Human Vascular Endothelial Growth Factor Internal Ribosomal Entry Site and Represses the Translation

G-quadruplexes are believed to have important biological functions, so many small molecules have been screened or developed for targeting G-quadruplexes. However, it is still a major challenge to find molecules that recognize specific G-quadruplexes. Here, by using a combination of surface plasmon r...

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Detalles Bibliográficos
Autores principales: Hu, Xiao-Xia, Wang, Sheng-Quan, Gan, Shi-Quan, Liu, Lei, Zhong, Ming-Qing, Jia, Meng-Hao, Jiang, Fei, Xu, Yan, Xiao, Chao-Da, Shen, Xiang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630693/
https://www.ncbi.nlm.nih.gov/pubmed/34858949
http://dx.doi.org/10.3389/fchem.2021.781198