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DNA Methylation Differences Between Zona Pellucida-Bound and Manually Selected Spermatozoa Are Associated With Autism Susceptibility

Children conceived through intracytoplasmic sperm injection (ICSI) have been reported to have a higher risk of many abnormalities and disorders, including autism and intellectual disability, which may be due to bypassing of the natural sperm selection process during ICSI. Zona pellucida (ZP)-bound s...

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Detalles Bibliográficos
Autores principales: Wang, Longda, Chen, Mengxiang, Yan, Gaofeng, Zhao, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630694/
https://www.ncbi.nlm.nih.gov/pubmed/34858344
http://dx.doi.org/10.3389/fendo.2021.774260