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Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

Type 1 diabetes (T1D) is a disease that arises due to complex immunogenetic mechanisms. Key cell-cell interactions involved in the pathogenesis of T1D are activation of autoreactive T cells by dendritic cells (DC), migration of T cells across endothelial cells (EC) lining capillary walls into the is...

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Detalles Bibliográficos
Autores principales: Armitage, Lucas H., Stimpson, Scott E., Santostefano, Katherine E., Sui, Lina, Ogundare, Similoluwa, Newby, Brittney N., Castro-Gutierrez, Roberto, Huber, Mollie K., Taylor, Jared P., Sharma, Prerana, Radichev, Ilian A., Perry, Daniel J., Fredette, Natalie C., Savinov, Alexei Y., Wallet, Mark A., Terada, Naohiro, Brusko, Todd M., Russ, Holger A., Chen, Jing, Egli, Dieter, Mathews, Clayton E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630743/
https://www.ncbi.nlm.nih.gov/pubmed/34858326
http://dx.doi.org/10.3389/fendo.2021.737276