Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies

The characterization of monoclonal antibodies (mAbs) requires laborious and time-consuming sample preparation steps before the liquid chromatography–mass spectrometry (LC-MS) analysis. Middle-up approaches entailing the use of specific proteases (papain, IdeS, etc.) emerged as practical and informat...

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Detalles Bibliográficos
Autores principales: Rinaldi, Francesca, Tengattini, Sara, Brusotti, Gloria, Tripodo, Giuseppe, Peters, Benjamin, Temporini, Caterina, Massolini, Gabriella, Calleri, Enrica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630785/
https://www.ncbi.nlm.nih.gov/pubmed/34859053
http://dx.doi.org/10.3389/fmolb.2021.765683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630785/
https://www.ncbi.nlm.nih.gov/pubmed/34859053
http://dx.doi.org/10.3389/fmolb.2021.765683

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