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miR-30a-5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β-catenin signaling in aplastic anemia

Aplastic anemia (AA) is a bone marrow failure syndrome with high morbidity and mortality. Bone marrow (BM)-mesenchymal stem cells (MSCs) are the main components of the BM microenvironment, and dysregulation of BM-MSC adipogenic differentiation is a pathologic hallmark of AA. MicroRNAs (miRNAs/miRs)...

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Detalles Bibliográficos
Autores principales: Wang, Enbo, Zhang, Yunyan, Ding, Rongmei, Wang, Xiaohua, Zhang, Shumin, Li, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630822/
https://www.ncbi.nlm.nih.gov/pubmed/34821370
http://dx.doi.org/10.3892/mmr.2021.12543