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Long non-coding RNA MIR17HG sponges microRNA-21 to upregulate PTEN and regulate homoharringtonine-based chemoresistance of acute myeloid leukemia cells

Long non-coding (lnc)RNA MIR17HG has been identified as a oncogene whose roles in acute myeloid leukemia (AML) remain unclear. The present study aimed to investigate the role of lncRNA MIR17HG in AML. Differential expression of MIR17HG in AML was determined by reverse transcription-quantitative PCR....

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Detalles Bibliográficos
Autores principales: Yan, Jinhua, Yao, Ling, Li, Ping, Wu, Guohe, Lv, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630824/
https://www.ncbi.nlm.nih.gov/pubmed/34868361
http://dx.doi.org/10.3892/ol.2021.13142