Exosomes for gene therapy effectively inhibit the endothelial-mesenchymal transition in mouse aortic endothelial cells

BACKGROUND: Heterotopic ossification (HO) can limit joint activity, causes ankylosis and impairs the function and rehabilitation of patients. Endothelial to mesenchymal transition (EndMT) plays an important role in the pathogenesis of HO, and high expression of SMAD7(Mothers Against Decapentaplegic...

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Detalles Bibliográficos
Autores principales: Wei, Zhenyuan, Zhao, Yang, Hsu, Peichun, Guo, Shang, Zhang, Chi, Zhong, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630863/
https://www.ncbi.nlm.nih.gov/pubmed/34847881
http://dx.doi.org/10.1186/s12891-021-04896-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630863/
https://www.ncbi.nlm.nih.gov/pubmed/34847881
http://dx.doi.org/10.1186/s12891-021-04896-0

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