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Tracing TET1 expression in prostate cancer: discovery of malignant cells with a distinct oncogenic signature

BACKGROUND: Ten–eleven translocation methylcytosine dioxygenase 1 (TET1) is involved in DNA demethylation and transcriptional regulation, plays a key role in the maintenance of stem cell pluripotency, and is dysregulated in malignant cells. The identification of cancer stem cells (CSCs) driving tumo...

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Detalles Bibliográficos
Autores principales: Schagdarsurengin, U., Luo, C., Slanina, H., Sheridan, D., Füssel, S., Böğürcü-Seidel, N., Gattenloehner, S., Baretton, G. B., Hofbauer, L. C., Wagenlehner, F., Dansranjav, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630881/
https://www.ncbi.nlm.nih.gov/pubmed/34844636
http://dx.doi.org/10.1186/s13148-021-01201-7