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Aberration-corrected ultrafine analysis of miRNA reads at single-base resolution: a k-mer lattice approach
Raw sequencing reads of miRNAs contain machine-made substitution errors, or even insertions and deletions (indels). Although the error rate can be low at 0.1%, precise rectification of these errors is critically important because isoform variation analysis at single-base resolution such as novel iso...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631080/ https://www.ncbi.nlm.nih.gov/pubmed/34291293 http://dx.doi.org/10.1093/nar/gkab610 |