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Tissue‐Specific Regulation of Ferroportin in Wild‐Type and Hjv‐/‐ Mice Following Dietary Iron Manipulations

Hepcidin is a liver‐derived peptide hormone that limits iron egress from tissues to the bloodstream. It operates by binding to the iron exporter ferroportin, which blocks iron transport and tags ferroportin for degradation. Genetic hepcidin inactivation leads to hereditary hemochromatosis, a disease...

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Detalles Bibliográficos
Autores principales: Katsarou, Angeliki, Gkouvatsos, Konstantinos, Fillebeen, Carine, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631100/
https://www.ncbi.nlm.nih.gov/pubmed/34558857
http://dx.doi.org/10.1002/hep4.1780