Cargando…

Umbelliferyloxymethyl phosphonate compounds-weakly binding zinc ionophores with neuroprotective properties

Umbelliferone is a member of the coumarin family of compounds which are known for diverse pharmacological activity including in targets relevant to Alzheimers disease, AD. The toxicity associated with some forms of the amyloid protein, Aβ, and the role of Zn(2+) (and other biometals) dyshomeostasis...

Descripción completa

Detalles Bibliográficos
Autores principales: Guesne, Sebastien, Connole, Laura, Kim, Stephanie, Motevalli, Majid, Robson, Lesley, Michael-Titus, Adina T., Sullivan, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631114/
https://www.ncbi.nlm.nih.gov/pubmed/34761777
http://dx.doi.org/10.1039/d1dt02298a