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Umbelliferyloxymethyl phosphonate compounds-weakly binding zinc ionophores with neuroprotective properties
Umbelliferone is a member of the coumarin family of compounds which are known for diverse pharmacological activity including in targets relevant to Alzheimers disease, AD. The toxicity associated with some forms of the amyloid protein, Aβ, and the role of Zn(2+) (and other biometals) dyshomeostasis...
Autores principales: | Guesne, Sebastien, Connole, Laura, Kim, Stephanie, Motevalli, Majid, Robson, Lesley, Michael-Titus, Adina T., Sullivan, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631114/ https://www.ncbi.nlm.nih.gov/pubmed/34761777 http://dx.doi.org/10.1039/d1dt02298a |
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