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Aristolochic Acid Induces Chronic Kidney Disease in ACE Knockout Mice

BACKGROUND: Aristolochic acid I (AAI) is an extract from Chinese herbs that causes progressive interstitial nephritis. The aim of this research is to know whether chymases play the crucial role in AAI-induced nephropathy. METHODS: The mice were treated with AAI via intraperitoneal injection and the...

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Detalles Bibliográficos
Autor principal: Wu, Jia-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631122/
https://www.ncbi.nlm.nih.gov/pubmed/34912527
http://dx.doi.org/10.4103/ijpvm.IJPVM_344_19