Clonorchis sinensis Granulin Promotes Malignant Transformation of Hepatocyte Through EGFR-Mediated RAS/MAPK/ERK and PI3K/Akt Signaling Pathways

The biological functions of growth factor, such as granulins, have been explored in parasites, and we elucidated that Clonorchis sinensis granulin (CsGRN) promoted the metastasis of hepatocellular carcinoma in our previous study. However, it is still unclear for the malignant transformation role of...

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Detalles Bibliográficos
Autores principales: Wang, Caiqin, He, Qing, Yin, Yingxuan, Wu, Yinjuan, Li, Xuerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631275/
https://www.ncbi.nlm.nih.gov/pubmed/34858869
http://dx.doi.org/10.3389/fcimb.2021.734750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631275/
https://www.ncbi.nlm.nih.gov/pubmed/34858869
http://dx.doi.org/10.3389/fcimb.2021.734750

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