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SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS

The COVID-19 is an infectious disease caused by SARS-CoV-2 infection. A large number of clinical studies found high-level expression of pro-inflammatory cytokines in patients infected with SARS-CoV-2, which fuels the rapid development of the disease. However, the specific molecular mechanism is stil...

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Detalles Bibliográficos
Autores principales: Li, Weiling, Qiao, Jialu, You, Qiang, Zong, Shan, Peng, Qian, Liu, Yuchen, Hu, Song, Liu, Wei, Li, Shufen, Shu, Xiji, Sun, Binlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631293/
https://www.ncbi.nlm.nih.gov/pubmed/34858407
http://dx.doi.org/10.3389/fimmu.2021.750969