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A Transcriptional Signature of IL-2 Expanded Natural Killer Cells Predicts More Favorable Prognosis in Bladder Cancer

Activation of natural killer (NK) cell function is regulated by cytokines, such as IL-2, and secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth factor D (PDGF-DD). In order to elucidate a clinical role for these important regulators of NK cell function in ant...

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Detalles Bibliográficos
Autores principales: Sun, Yuhan, Sedgwick, Alexander James, Khan, Md Abdullah-Al-Kamran, Palarasah, Yaseelan, Mangiola, Stefano, Barrow, Alexander David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631443/
https://www.ncbi.nlm.nih.gov/pubmed/34858395
http://dx.doi.org/10.3389/fimmu.2021.724107