Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice

NLRP3 inflammasome activation contributes to several pathogenic conditions, including lipopolysaccharide (LPS)-induced sickness behavior characterized by reduced mobility and depressive behaviors. Dimethyl fumarate (DMF) is an immunomodulatory and anti-oxidative molecule commonly used for the sympto...

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Detalles Bibliográficos
Autores principales: Tastan, Bora, Arioz, Burak I., Tufekci, Kemal Ugur, Tarakcioglu, Emre, Gonul, Ceren Perihan, Genc, Kursad, Genc, Sermin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631454/
https://www.ncbi.nlm.nih.gov/pubmed/34858398
http://dx.doi.org/10.3389/fimmu.2021.737065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631454/
https://www.ncbi.nlm.nih.gov/pubmed/34858398
http://dx.doi.org/10.3389/fimmu.2021.737065

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