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Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice

NLRP3 inflammasome activation contributes to several pathogenic conditions, including lipopolysaccharide (LPS)-induced sickness behavior characterized by reduced mobility and depressive behaviors. Dimethyl fumarate (DMF) is an immunomodulatory and anti-oxidative molecule commonly used for the sympto...

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Detalles Bibliográficos
Autores principales:	Tastan, Bora, Arioz, Burak I., Tufekci, Kemal Ugur, Tarakcioglu, Emre, Gonul, Ceren Perihan, Genc, Kursad, Genc, Sermin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631454/ https://www.ncbi.nlm.nih.gov/pubmed/34858398 http://dx.doi.org/10.3389/fimmu.2021.737065

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