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Deciphering the molecular mechanism of the cancer formation by chromosome structural dynamics

Cancer reflects the dysregulation of the underlying gene network, which is strongly related to the 3D genome organization. Numerous efforts have been spent on experimental characterizations of the structural alterations in cancer genomes. However, there is still a lack of genomic structural-level un...

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Detalles Bibliográficos
Autores principales: Chu, Xiakun, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631624/
https://www.ncbi.nlm.nih.gov/pubmed/34752443
http://dx.doi.org/10.1371/journal.pcbi.1009596