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Stability evaluation of compounded clonidine hydrochloride oral liquids based on a solid-phase extraction HPLC-UV method

The present study aimed to assess the stability of clonidine hydrochloride oral liquids (20-μg/mL) prepared from two different generic tablets in Ora-Blend and stored in amber plastic bottles. Physical and chemical stabilities were evaluated over a period of 90 days at 25°C. Analytical challenges we...

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Detalles Bibliográficos
Autores principales: Coache, Daphné, Friciu, Mihaela, Roullin, V. Gaëlle, Boulé, Marianne, Forest, Jean-Marc, Leclair, Grégoire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631633/
https://www.ncbi.nlm.nih.gov/pubmed/34847160
http://dx.doi.org/10.1371/journal.pone.0260279