Cargando…
Avidity observed between a bivalent inhibitor and an enzyme monomer with a single active site
Although myriad protein–protein interactions in nature use polyvalent binding, in which multiple ligands on one entity bind to multiple receptors on another, to date an affinity advantage of polyvalent binding has been demonstrated experimentally only in cases where the target receptor molecules are...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631645/ https://www.ncbi.nlm.nih.gov/pubmed/34847142 http://dx.doi.org/10.1371/journal.pone.0249616 |