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Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy

Lung cancer is the leading cause of cancer-related deaths. While the recent use of immune checkpoint inhibitors significantly improves patient outcomes, responsiveness remains restricted to a small proportion of patients. Conventional dendritic cells (DCs) play a major role in anticancer immunity. I...

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Detalles Bibliográficos
Autores principales: Brassard, Julyanne, Gill, Meredith Elizabeth, Bernatchez, Emilie, Desjardins, Véronique, Roy, Joanny, Joubert, Philippe, Marsolais, David, Blanchet, Marie-Renée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631683/
https://www.ncbi.nlm.nih.gov/pubmed/34847189
http://dx.doi.org/10.1371/journal.pone.0260636