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Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy
Lung cancer is the leading cause of cancer-related deaths. While the recent use of immune checkpoint inhibitors significantly improves patient outcomes, responsiveness remains restricted to a small proportion of patients. Conventional dendritic cells (DCs) play a major role in anticancer immunity. I...
Autores principales: | Brassard, Julyanne, Gill, Meredith Elizabeth, Bernatchez, Emilie, Desjardins, Véronique, Roy, Joanny, Joubert, Philippe, Marsolais, David, Blanchet, Marie-Renée |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631683/ https://www.ncbi.nlm.nih.gov/pubmed/34847189 http://dx.doi.org/10.1371/journal.pone.0260636 |
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