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Asparagine Tautomerization in Glycosyltransferase Catalysis. The Molecular Mechanism of Protein O-Fucosyltransferase 1

[Image: see text] O-glycosylation is a post-translational protein modification essential to life. One of the enzymes involved in this process is protein O-fucosyltransferase 1 (POFUT1), which fucosylates threonine or serine residues within a specific sequence context of epidermal growth factor-like...

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Detalles Bibliográficos
Autores principales: Piniello, Beatriz, Lira-Navarrete, Erandi, Takeuchi, Hideyuki, Takeuchi, Megumi, Haltiwanger, Robert S., Hurtado-Guerrero, Ramón, Rovira, Carme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631701/
https://www.ncbi.nlm.nih.gov/pubmed/34868727
http://dx.doi.org/10.1021/acscatal.1c01785