Cargando…

Carfilzomib: A Promising Proteasome Inhibitor for the Treatment of Relapsed and Refractory Multiple Myeloma

The proteasome is crucial for the degradation of intracellular proteins and plays an important role in mediating a number of cell survival and progression events by controlling the levels of key regulatory proteins such as cyclins and caspases in both normal and tumor cells. However, compared to nor...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayaweera, Shansa Pranami E., Wanigasinghe Kanakanamge, Sacheela Prasadi, Rajalingam, Dharshika, Silva, Gayathri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631731/
https://www.ncbi.nlm.nih.gov/pubmed/34858819
http://dx.doi.org/10.3389/fonc.2021.740796