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Overt Acute Hepatitis B Deteriorates in Females: Destructive Immunity With an Exaggerated Interleukin-17 Pathway

BACKGROUND AND AIMS: We previously showed that overt acute hepatitis B (AHB) was more severe in female patients. Using the same cohort and AHB mouse model, we examined the underlying mechanism. METHODS: Baseline biochemistry, virological and cytokine assays, and T helper (Th)1 and Th2 immune markers...

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Detalles Bibliográficos
Autores principales: Chang, Ming-Ling, Yeh, Chau-Ting, Chien, Rong-Nan, Liaw, Yun-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631789/
https://www.ncbi.nlm.nih.gov/pubmed/34858385
http://dx.doi.org/10.3389/fimmu.2021.631976