A Novel Mutation of the KLK6 Gene in a Family With Knee Osteoarthritis

To investigate the correlation between gene mutation and knee osteoarthritis (KOA), a whole-exome sequencing (WES) was applied to analyze blood samples of four KOA patients and two normal subjects in a family. Gene mutations were identified by gene-trapping and high-throughput sequencing analysis ac...

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Detalles Bibliográficos
Autores principales: Ge, Yanzhi, Zhou, Chenfen, Xiao, Xiujuan, Jin, Zhijiang, Zhou, Li, Chen, Zuxiang, Liu, Fucun, Yuan, Qiang, Zhang, Guoqing, Shan, Letian, Tong, Peijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631809/
https://www.ncbi.nlm.nih.gov/pubmed/34858488
http://dx.doi.org/10.3389/fgene.2021.784176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631809/
https://www.ncbi.nlm.nih.gov/pubmed/34858488
http://dx.doi.org/10.3389/fgene.2021.784176

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