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Matrix Stiffening Enhances DNCB-Induced IL-6 Secretion in Keratinocytes Through Activation of ERK and PI3K/Akt Pathway

Matrix stiffness, a critical physical property of the cellular environment, is implicated in epidermal homeostasis. In particular, matrix stiffening during the pathological progression of skin diseases appears to contribute to cellular responses of keratinocytes. However, it has not yet elucidated t...

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Detalles Bibliográficos
Autores principales: Chung, Hyewon, Oh, Seunghee, Shin, Hyun-Woo, Lee, Yunam, Lee, Hyungsuk, Seok, Seung Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631934/
https://www.ncbi.nlm.nih.gov/pubmed/34858412
http://dx.doi.org/10.3389/fimmu.2021.759992