Glutamine deprivation triggers NAGK-dependent hexosamine salvage

Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylation in the cell. Prior studies have identified the...

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Detalles Bibliográficos
Autores principales: Campbell, Sydney, Mesaros, Clementina, Izzo, Luke, Affronti, Hayley, Noji, Michael, Schaffer, Bethany E, Tsang, Tiffany, Sun, Kathryn, Trefely, Sophie, Kruijning, Salisa, Blenis, John, Blair, Ian A, Wellen, Kathryn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
https://www.ncbi.nlm.nih.gov/pubmed/34844667
http://dx.doi.org/10.7554/eLife.62644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
https://www.ncbi.nlm.nih.gov/pubmed/34844667
http://dx.doi.org/10.7554/eLife.62644

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